Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Image Caption: Technologies evolved related to the Human Genome Project. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Researchers announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...